Diabetes is a serious condition that can affect the eyes, heart, nerves, feet, and kidneys.
diabetescan affect many major organs, such as the heart, eyes, kidneys and brain. When the disease is not well controlled, it can cause many serious comorbidities, which are conditions that occur together with diabetes. For people with type 1 and type 2 diabetes, finding a treatment plan that works is vital to avoid these problems.
The heart is part of the cardiovascular or circulatory system. This body system also includes blood vessels, which carry oxygen and nutrients to organs and tissues. Blood vessels also help eliminate carbon dioxide, toxins, and waste. The American Heart Association lists diabetes as one of the seven major controllable risk factors for cardiovascular disease (CVD).
CVDs include all types of heart disease, stroke, and blood vessel disease. Over time, diabetes can also damage the blood vessels and nerves that control the heart. The longer you have diabetes, the greater your chances of developing heart disease. The kidneys work like a filtration system.
They remove waste, excess fluid and acid from the body. Healthy kidneys help maintain a good balance of water, salts and minerals in the blood. The kidneys also produce vitamin D and erythropoietin. Vitamin D helps the body absorb calcium and promotes a healthy immune system.
Erythropoietin is a hormone that stimulates the production of red blood cells. Over time, high blood sugar levels caused by diabetes can damage the blood vessels in the kidneys. This can affect your ability to cleanse your body and cause waste and fluids to build up in your blood. This type of kidney disease is known as diabetic nephropathy.
Studies have shown that people with diabetes have lower levels of density and volume of gray matter in various parts of the brain. Gray matter is an important part of the central nervous system. It plays a role in everyday functioning. Reducing the density or volume of gray matter can affect a variety of brain and nerve functions.
Diabetes can also damage small blood vessels in the brain. This can lead to strokes or the death of brain tissue. Some studies suggest that medications that treat low blood sugar levels may contribute to lung disease in people with diabetes. One discovered that different medications can affect the lungs in different ways.
For example, the common diabetes drug Glucophage (metformin) is thought to work against lung diseases, while insulin may worsen lung disease. Type 1 diabetes is caused by this lack of insulin production. Type 2 diabetes, on the other hand, occurs when the body develops resistance to insulin. This puts pressure on the pancreas as it tries to produce more insulin than it normally needs.
When you have uncontrolled diabetes, you are at greater risk for several health problems. These problems can affect major organs and organ systems, such as the heart and blood vessels, kidneys, lungs, pancreas, digestive system, and brain. Uncontrolled blood sugar can also affect the mouth and teeth, eyes, skin, and sexual organs. It's important to note that diabetes can put you at risk for potentially life-threatening conditions, such as heart disease, pancreatic cancer, and kidney failure.
. Diabetes affects the heart and the entire circulation. This includes the small blood vessels in the kidneys, eyes and nerves, and the large ones that feed the heart and brain and keep it alive. Effects of type 2 diabetes mellitus on body organs.
Type 2 diabetes is an inflammatory condition that affects the circulatory system, gastrointestinal tract, pancreatic beta cells, liver and skeletal muscles and makes them dysfunctional. NFALD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; ER, endoplasmic reticulum. Other parts of the body can also be affected by diabetes, such as the digestive system, skin, sexual organs, teeth and gums, and the immune system. Because diabetes affects blood flow and the immune system, a small sore may not get what it needs to heal.
Hyperglycemia alters the normal functions of the circulatory system, gastrointestinal tract, pancreatic beta cells, liver, and skeletal muscles to increase systemic insulin resistance. Type 2 diabetes, the most common form of diabetes (~ 90%), is characterized by a systemic inflammatory disease accompanied by insulin resistance (IR) or a decrease in the metabolic response to insulin in several tissues, including adipose tissue, liver and skeletal muscle, as well as by a reduction in insulin synthesis by beta cells of the pancreas (4,. Adaptive immunity is mediated by B cells, which produce antibodies, and T cells, which are classified as CD4+ helper cells and cytotoxic CD8+ cells. Virtually all parts of the human digestive system, including the gastrointestinal tract, pancreas, and liver, are affected by diabetes.
Hyperglycemia and subsequent inflammation are the main causes of micro and macroangiopathies in the circulatory system. In a model system, mice with type 2 diabetes have reduced amounts of specific antibodies against Staphylococcus aureus (both total and IgG), which will increase the risk of infection and morbidity in diabetic mice. However, the ability of dysfunctional glycosylated antibodies to neutralize viruses is impaired, increasing susceptibility to infections. The field of immunometabolism involves a bidirectional link between the immune system and metabolism, in which inflammation plays an essential role in promoting metabolic abnormalities (e.g.
Mucosal barriers, such as intestinal epithelial cells (IEC) and the mucosal layer, spatially isolate the host's immune system and gut microbiota to prevent unnecessary immune activation and intestinal inflammation. Diabetes can affect many different organs and systems and cause other diseases that adversely affect health. Effects of type 2 diabetes mellitus on biochemical markers, as well as on the circulatory, digestive and muscular systems. Obesity as the main inducer of low-level systemic inflammation is one of the main factors of susceptibility to type 2 diabetes.
Diabetes also impairs the immune system and increases patients' susceptibility to serious and long-term infections (20). .