Diabetes affects the heart and the entire circulation. This includes the small blood vessels in the kidneys, eyes and nerves, and the large ones that feed the heart and brain and keep it alive. The damage starts with high blood sugar (glucose) and insulin levels.
Diabetescan affect many important organs, such as the heart, eyes, kidneys and brain.
When the disease is not well controlled, it can cause many serious comorbidities, which are conditions that occur together with diabetes. For people with type 1 and type 2 diabetes, finding a treatment plan that works is vital to avoid these problems. Diabetes causes diabetic neuropathy or nerve damage. This can affect your perception of heat, cold, and pain.
It can also make you more susceptible to injury. In a person with diabetes, the pancreas cannot produce insulin or cannot produce enough insulin to regulate blood sugar. Without insulin, the body can't use glucose as an energy source. To replace the energy normally obtained from glucose, the body must break down fat, causing the build-up of a toxic byproduct known as ketones.
Over time, this results in diabetic ketoacidosis, a potentially life-threatening condition in which excess ketones cause the blood to be too acidic. Both alpha and beta cells in the pancreas play a central role in controlling blood sugar. Alpha cells increase the amount of glucagon produced. Glucagon is a hormone that plays a role in converting glycogen stored in the liver and muscles back into glucose (sugar).
Cells use this glucose as energy to do their work. 1 The fat cells of people with type 2 diabetes break down more fats and other lipids. This leads to high blood sugar levels, which leads to insulin resistance. Insulin resistance is what happens when the body doesn't respond to insulin the way it should.
1 The liver is one of the main places where the body stores sugar. Diabetes causes the liver to compensate for the body's decreased ability to absorb sugar and use it as energy. It does this by producing more sugar. 1.This can cause high levels of toxic chemicals, including acids and ketone bodies, which can cause a condition called diabetic ketoacidosis.